منابع مشابه
Whither brown fat?
In 1551 Gessner described a lobular fatty tissue which we now know as brown adipose tissue (BAT). Apart from a few descriptions of the tissue in hibernators, it was then virtually ignored by scientists for the next four hundred years until its involvement in the thermoregulation of non-hibernating mammals was suggested (Smith, 1961). However, even after this work in the early 1960s, doubts over...
متن کاملBrown fat and thermogenesis.
Historical Background. ..................................................... 330 PhylogeneticDistribution .................................................. 332 AnatomyandTopology ................................................... 333 Vasculature of Brown Adipose Tissue. ...................................... 338 Microcirculation and vascularity .......................................... 338 G...
متن کاملDietary fat overload reprograms brown fat mitochondria
Chronic nutrient overload accelerates the onset of several aging-related diseases reducing life expectancy. Although the mechanisms by which overnutrition affects metabolic processes in many tissues are known, its role on BAT physiology is still unclear. Herein, we investigated the mitochondrial responses in BAT of female mice exposed to high fat diet (HFD) at different steps of life. Although ...
متن کاملStress prompts habit behavior in humans.
Instrumental behavior can be controlled by goal-directed action-outcome and habitual stimulus-response processes that are supported by anatomically distinct brain systems. Based on previous findings showing that stress modulates the interaction of "cognitive" and "habit" memory systems, we asked in the presented study whether stress may coordinate goal-directed and habit processes in instrument...
متن کاملBrown fat - hotting up again.
For a decade or so from the late 1970s brown adipose tissue was a key focus of obesity research. The concept that adaptive changes in energy expenditure are important in the regulation of energy balance, with reductions in thermogenesis as a major factor in the development of obesity, had taken centre stage. This was based on some pivotal observations from studies on experimental animals. Brown...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2014
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2014.07.017